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Just one or multiple drug overdose with oxycodone and acetaminophen is a potentially lethal polydrug overdose, and session by using a regional poison control Middle is suggested.In this case, mixed agonist/antagonist analgesics might decrease the analgesic impact of oxycodone and/or might precipitate withdrawal signs or symptoms in these patients.D

Lamotrigine: Serum lamotrigine concentrations might be lessened, manufacturing a minimize in therapeutic results.In this situation, combined agonist/antagonist analgesics may well reduce the analgesic influence of oxycodone and/or may possibly precipitate withdrawal signs and symptoms in these sufferers.Within a pharmacokinetic examine of oxycodone